{"id":13414,"date":"2025-08-29T13:29:00","date_gmt":"2025-08-29T11:29:00","guid":{"rendered":"https:\/\/fbhi.devcx.com\/network-project\/in-tempo-italy\/"},"modified":"2025-10-27T15:17:29","modified_gmt":"2025-10-27T14:17:29","slug":"in-tempo-italy","status":"publish","type":"network-project","link":"https:\/\/fbhi.devcx.com\/sv\/network-project\/in-tempo-italy\/","title":{"rendered":"IN-TeMPO (Italy)"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column top_padding_desktop=&#8221;0&#8243; bottom_padding_desktop=&#8221;0&#8243; left_padding_desktop=&#8221;0&#8243; right_padding_desktop=&#8221;0&#8243; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;5px&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/6&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_color=&#8221;#006885&#8243; column_border_style=&#8221;solid&#8221; column_padding_type=&#8221;advanced&#8221; gradient_type=&#8221;default&#8221;][image_with_animation image_url=&#8221;13155&#8243; image_size=&#8221;medium_large&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;5px&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;lazy-load&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][\/vc_column][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;left&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;4\/6&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; column_padding_type=&#8221;default&#8221; gradient_type=&#8221;default&#8221;][vc_column_text css=&#8221;.vc_custom_1757080031124{margin-right: 0px !important;padding-top: 80px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;}&#8221;]\n<h4>ItaliaN Study With Tailored Multidomain Interventions to Prevent Functional and Cognitive Decline in Community-dwelling Older Adults (IN-TeMPO)<\/h4>\n[\/vc_column_text][\/vc_column][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/6&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column top_padding_desktop=&#8221;0&#8243; bottom_padding_desktop=&#8221;0&#8243; left_padding_desktop=&#8221;0&#8243; right_padding_desktop=&#8221;30&#8243; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;5px&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;2\/3&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_color=&#8221;#006885&#8243; column_border_style=&#8221;solid&#8221; column_padding_type=&#8221;advanced&#8221; gradient_type=&#8221;default&#8221;][vc_column_text css=&#8221;.vc_custom_1756726393825{margin-right: 50px !important;border-top-width: 1px !important;border-right-width: 1px !important;border-bottom-width: 1px !important;border-left-width: 1px !important;padding-top: 6px !important;padding-right: 6px !important;padding-bottom: 6px !important;padding-left: 7px !important;border-left-color: #e3a883 !important;border-left-style: solid !important;border-right-color: #e3a883 !important;border-right-style: solid !important;border-top-color: #e3a883 !important;border-top-style: solid !important;border-bottom-color: #e3a883 !important;border-bottom-style: solid !important;border-radius: 5px !important;}&#8221;]\n<div id=\"brief-summary\" class=\"study-overview-item-text overview-col-wide\">\n<p>The IN-TeMPO study investigates the effects of an active, guided multi-domain intervention compared to a self-guided intervention followed by normal clinical practice. The primary objective is whether these interventions can prevent functional and cognitive decline in older adults at risk of cognitive decline. The intervention includes the same five lifestyle domains as the FINGER study as well as novel factors such as oral hygiene, vision and hearing, and sleep. A comprehensive set of laboratory biomarkers will be measured to gain new insights into underlying mechanisms and to further support the development of prevention and early detection strategies.   <\/p>\n<\/div>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1757080632988{margin-right: 0px !important;padding-top: 0px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;}&#8221;]<em>Latest page update: 5 September, 2025<\/em>[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713428474{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Aim of the project<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713420948{margin-right: 50px !important;}&#8221;]To investigate the effects of a multi-domain intervention ( &#8221;active intervention&#8221;), compared to that followed by normal clinical practice (&#8221;self-guided intervention&#8221;), in older adults. The primary objective is whether these interventions can prevent functional and cognitive decline in at-risk subjects.[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756283848827{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Location<\/h5>\n[\/vc_column_text][vc_column_text]Nine clinical centers across north, central, and south Italy: Monza, Novara, Florence, Rome, Naples, Bari, Catania, Palermo, and Molise.[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756297816087{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Local setting<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713666418{margin-right: 50px !important;}&#8221;]Recruitment has taken place both at clinical centers, through internal referral and\/or advertising on local newspapers, and at general practitioners.<br \/>\nThe trial was designed to draw from both major urban centers and rural areas in order to ensure a diverse representation.[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756394056752{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Leading organization<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713691464{margin-right: 50px !important;}&#8221;]University of Milano-Bicocca[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1750944520112{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Principal Investigator (PI)<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713725399{margin-right: 50px !important;}&#8221;]Carlo Ferrarese, University of Milano-Bicocca[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756298026049{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Research team<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713939559{margin-right: 50px !important;}&#8221;]University of Milano-Bicocca:<br \/>\nLuca Cuffaro<br \/>\nFederico Emanuele Pozzi<br \/>\nGessica Sala[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756285820979{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Duration of the intervention<\/h5>\n[\/vc_column_text][vc_column_text]12 months[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756305270248{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Project start date<\/h5>\n[\/vc_column_text][vc_column_text]2024[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756305197166{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Project end date<\/h5>\n[\/vc_column_text][vc_column_text]2026[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756286177804{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Current stage of the project<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756713989638{margin-right: 700px !important;border-radius: 5px !important;}&#8221;]Ongoing[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756286650835{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Number of study participants<\/h5>\n[\/vc_column_text][vc_column_text]1,534 estimated; 835 enrolled[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756286716985{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Target population<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756714094577{margin-right: 50px !important;}&#8221;]Community-dwelling older adults aged 60 years or more with mild to moderate frailty. In addition, presence of family history of dementia, and\/or at least one modifiable risk factor of dementia.[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756394875535{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Primary outcome<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756714122073{margin-right: 60px !important;}&#8221;]Change in global cognition assessed by mNTB, a battery of cognitive tests[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756394999258{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Secondary outcomes<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756714167625{margin-right: 60px !important;}&#8221;]\n<ul>\n<li>Individual cognitive domains<\/li>\n<li>Physical activity<\/li>\n<li>Cognitive and functional levels<\/li>\n<li>Resilience<\/li>\n<li>Falls<\/li>\n<li>Depressive symptoms<\/li>\n<li>Loneliness<\/li>\n<li>Quality of life and well-being<\/li>\n<li>Sleep quality<\/li>\n<li>Nutrition<\/li>\n<li>Biomarkers: APOE genotype, p-tau217, NfL, GFAP, IL-6, etc.<\/li>\n<\/ul>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1750944578157{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Intervention<\/h5>\n[\/vc_column_text][vc_column_text]<strong>This study has 2 arms:<\/strong><\/p>\n<ul>\n<li>Multidomain intervention<\/li>\n<li>Self-guided intervention (control group): participants receive suggestions through app-web or video tutorials on the same domains<\/li>\n<\/ul>\n[\/vc_column_text][vc_column_text]<strong>\u2514 Multidomain intervention<\/strong><\/p>\n<ul>\n<li>Physical exercise<\/li>\n<li>Nutrition: Mediterranean diet-based nutritional plan<\/li>\n<li>Cognitive training: using BrainHQ program<\/li>\n<li>Monitoring of cardiovascular risk factors<\/li>\n<li>Oral hygiene<\/li>\n<li>Monitoring and counselling on visual and auditory abilities<\/li>\n<li>Sleep hygiene<\/li>\n<li>Social interactions<\/li>\n<\/ul>\n[\/vc_column_text][vc_column_text]<strong>Digital solutions<\/strong><\/p>\n<ul>\n<li>BrainHQ is a self-adapting cognitive training software, scientifically validated from previous studies. It is provided to the participants of the intervention group. Participants have the possibility of receiving a tablet to run the software in case of need.  <\/li>\n<li>A specific website has been created for the self-guided group, with educational materials ordered to be delivered in a precise temporal sequence to maintain compliance to the study.<\/li>\n<li>A wearable tracker (Garmin Vivosmart) will collect movement data (steps, pace, speed, and activity types) and cardiac data (heart rate, heart rate variability), scientifically validated from previous studies. The device is given to enrolled subjects for the first and last month of participation. <\/li>\n<li>A digital coach is appointed for each recruitment center to help enrolled subjects in approaching the digital tools<\/li>\n<\/ul>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756715921870{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Results<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756715936863{margin-right: 60px !important;}&#8221;]Results have not yet been published.[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756304280464{margin-right: 50px !important;padding-top: 1px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 1px !important;background-color: rgba(227,168,131,0.52) !important;*background-color: rgb(227,168,131) !important;border-radius: 4px !important;}&#8221;]\n<h5>Acknowledgements<\/h5>\n[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756715127110{margin-right: 60px !important;}&#8221;]Funding from Next Generation EU, in the context of the National Recovery and Resilience Plan, Investment PE8 \u2013 Project Age-It: \u201cAgeing Well in an Ageing Society\u201d [DM 1557 11.10.2022, CUP: H43C22000840006].[\/vc_column_text][vc_column_text css=&#8221;.vc_custom_1756284734132{margin-right: 40px !important;}&#8221;][\/vc_column_text][\/vc_column][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/3&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][image_with_animation image_url=&#8221;13089&#8243; image_size=&#8221;full&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;5px&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;lazy-load&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;1&#8243;][vc_column_text css=&#8221;.vc_custom_1756715770373{border-top-width: 1px !important;border-right-width: 1px !important;border-bottom-width: 1px !important;border-left-width: 1px !important;padding-top: 5px !important;padding-right: 5px !important;padding-bottom: 5px !important;padding-left: 7px !important;border-left-color: #dd9933 !important;border-left-style: solid !important;border-right-color: #dd9933 !important;border-right-style: solid !important;border-top-color: #dd9933 !important;border-top-style: solid !important;border-bottom-color: #dd9933 !important;border-bottom-style: solid !important;border-radius: 5px !important;}&#8221;]<strong>Registered trial: <\/strong><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06248723\" target=\"_blank\" rel=\"noopener\">ItaliaN Study With Tailored Multidomain Interventions to Prevent Functional and Cognitive Decline in Community-dwelling Older Adults (IN TeMPO)<\/a> (ClinicalTrials.gov)<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40400914\/\">Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network)<\/a> (Front Aging Neuroscience, 2025)[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>FINGER interventions, including novel risk factors, to investigate the effect in older adults in Italy. <\/p>\n","protected":false},"featured_media":13090,"template":"","class_list":["post-13414","network-project","type-network-project","status-publish","has-post-thumbnail","network-project-category-ongoing-sv"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.1.1 - 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